Cyclosporin-A Treatment in Steroid Nonresponsive Nephrotic Syndrome
نویسندگان
چکیده
منابع مشابه
Cyclosporin A in steroid-sensitive nephrotic syndrome with frequent relapses.
Eight patients with steroid-sensitive nephrotic syndrome which frequently relapsed despite cyclophosphamide treatment were given cyclosporin A (7.5 mg/kg/day to 10 mg/kg/day) for 8 to 12 weeks. Six had minimal change glomerulonephritis and two had focal segmental glomerulonephritis. Cyclosporin A was given to 5 patients when their nephrotic syndrome was in relapse and to 3 patients when the nep...
متن کاملChildren with Steroid-resistant Nephrotic Syndrome: a Single-Center Study
Background and Aim: Steroid-resistant nephrotic syndrome (SRNS) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. These patients are at risk of developing end-stage renal disease. The aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with SRNS.Materials and Met...
متن کاملTacrolimus treatment for steroid- and cyclosporin-resistant minimal-change nephrotic syndrome.
not be reversed. The patient developed massive Introduction oedema, pleural effusions and finally pulmonary oedema, associated with a gain of body weight of 25 kg Minimal-change glomerulonephritis (MCGN) is the despite the administration of high doses of loop diurmost frequent cause of nephrotic syndrome in children, etics. A maximum of urinary protein excretion of 62 g while in adults only 25%...
متن کاملRemission of idiopathic nephrotic syndrome after treatment with cyclosporin A.
Nephrotic syndrome in minimal change lipoid nephrosis and focal segmental glomerulosclerosis may be due to alteration of glomerular anionic sites by a lymphokine. Six adults with nephrotic syndrome who were resistant to treatment with corticosteroids and immunosuppressants were treated with cyclosporin A. In three patients with minimal change lipoid nephrosis who had been nephrotic for 3.5 to 2...
متن کاملTreatment of steroid-resistant pediatric nephrotic syndrome
Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the first line of treatment. A significant number of patients with SRNS progress to end-stage renal disease if remission is not achieved. For these chi...
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ژورنال
عنوان ژورنال: Paediatrica Indonesiana
سال: 2018
ISSN: 2338-476X,0030-9311
DOI: 10.14238/pi34.1-2.1994.1-7